Ultra Medica Pharmaceutical Industries







Products » » Respiratory Tract Drugs

Product Search

Drug Index A to Z

All 0-9 A B C D E F G H I J K L M N O P Q R S T U V W X Y Z

Deslomar ( Desloratadin )

  • Effective Material
    Desloratadin 2.5 mg
  • Caliber
    2.5 mg
  • Pharmacologic Form
    - Antihistamine
  • Therapeutic Categories
    Respiratory Tract Drugs
  • Pharmaceutical Form
Deslomar Syrup is containing 2.5 mg/5 mL desloratadine.
Pharmacodynamics properties
Desloratadine is a long-acting tricyclic histamine antagonist with selective H 1 -receptor histamine antagonist activity.
Food had no effect on the bioavailability (AUC and C max ) of DESLOMAR Syrup. Metabolism: Desloratadine (a major metabolite of loratadine) is extensively metabolized to 3-hydroxydesloratadine, an active metabolite, which is subsequently glucuronidated. Elimination: The mean elimination half-life of desloratadine was 27 hours.
Therapeutic indications
Seasonal Allergic Rhinitis: DESLOMAR is indicated for the relief of the nasal and non-nasal symptoms of seasonal allergic rhinitis.
Perennial Allergic Rhinitis: DESLOMAR is indicated for the relief of the nasal and non-nasal symptoms of perennial allergic rhinitis.
Chronic Idiopathic Urticaria: DESLOMAR is indicated for the symptomatic relief of pruritus, reduction in the number of hives, and size of hives, in patients with chronic idiopathic urticaria 6 months of age and older.
Side effect
in subjects 6 to 11 years of age, no individual adverse event was reported. may sometimes occurs pharyngitis, dry mouth, somnolence, and fatigue.
DESLOMAR Tablets 5 mg are contraindicated in patients who are hypersensitive to this medication or to any of its ingredients, or to loratadine.
Warnings and precautions
Carcinogenesis, Mutagenesis, Impairment of Fertility: The clinical significance of these findings during long-term use of desloratadine is not known.
Pregnancy and lactation
Pregnancy Category C: There are, however, no adequate and well-controlled studies in pregnant women. Desloratadine should be used during pregnancy only if clearly needed.
Nursing Mothers: Desloratadine passes into breast milk; therefore a decision should be made whether to discontinue nursing or to discontinue desloratadine, taking into
Drug interactions
Clinical pharmacology studies showed that desloratadine was coadministered with erythromycin, ketoconazole, azithromycin, or fluoxetine. Although increased plasma concentrations (C max) of desloratadine and 3-hydroxydesloratadine were observed, there were no clinically relevant changes in the safety profile of desloratadine.
Adults and children 12 years of age and over: DESLOMAR Syrup is 2 teaspoonfuls (5 mg in 10 mL) once daily.
Children 6 to 11 years of age: DESLOMAR Syrup is 1 teaspoonful (2.5 mg in 5 mL) once daily.
Children 12 months to 5 years of age: DESLOMAR Syrup is ½ teaspoonful (1.25 mg in 2.5 mL) once daily.
Children 6 to 11 months of age: DESLOMAR Syrup is 2 mL (1.0 mg) once daily.
There was an increase in mean heart rate. Desloratadine and 3-hydroxydesloratadine are not eliminated by hemodialysis.
A glass botile of 125ml packed in carton box.