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Sun D3 10000 ( Colecalciferol )

  • Effective Material
    Colecalciferol 10000 IU
  • Caliber
    10000 IU
  • Therapeutic Categories
    Vitamins & Minerals
  • Pharmaceutical Form
    Capsules
Composition : Sun-D3 10000 contains 10000 IU of vitamin D3 (Colecalciferol).
Pharmacokinetics : Distribution: Primarily hepatic
Protein binding: Extensively to vitamin D-binding protein
Metabolism: Primary liver and kidney hydroxylation; glucuronidation.
Half-life elimination: 14 hours.
Time to peak, plasma: 11 hours.
Excretion: As metabolites, urine (4.2 %) and feces (4.9 %).
Therapeutic indications : - Treatment of vitamin D deficiency.
- Dietary supplement for the treatment and prophylaxis of osteoporosis.
- Prophylaxis of deficiency (recent studies shown that vitamin D3 deficiency more prevalence in a lot of patients, and it’s strong relationship with diseases of elderly, women, and cardiovascular diseases, diabetes mellitus, hypertension, Multiple sclorosis, cancer.
Side effect :
Frequency not defined: Hypervitaminosis D (signs and symptoms include increase in blood phosphate or hypercalcemia, calciuria, headache, nausea, vomiting, vertigo, lethargy, polyuria, diarrhea or constipation and polydipsia)..
Contraindication : Hypercalcemia; hypersensitivity to cholecalciferol or any component of the formulation; malabsorption syndrome; evidence of vitamin D toxicity
Warnings & precautions : The levels of plasma calcium should be monitored especially in patients who are vulnerable to hypercalcemia.
Pregnancy & lactation : PREGNANCY:
Pregnancy Category C.

NURSING MOTHERS:
Enters breast milk. should be used cautiously during lactation.
Drug interactions :
- Don't co-administer with Orlistat or Olestra.
- Ethanol, Nutrition, and herbs may impair vitamin D absorption.
- People who use cardiac glycosides (digoxin) or thiazide diuretics should consult a physician before using supplemental vitamin D.
- Some antiepileptics increase vitamin D demand such as: carbamazepine, phenytoin, and Phenobarbital.
- Fat malabsorption decreases vitamin D absorption.
Dosage & administration : Sun-D3 10000: Take one capsule weekly.
or as recommended by a the physician.
Package : Sun-D3 5000:
1 blisters x 10 Capsules per Box with inserted leaflets.
Storage : Store at 15-30°C.
Keep away from reach of children.